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使用 'IGF-1R' 作为标签的产品

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AG-1024 (Tyrphostin)

Catalog No. A11400
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IGF-1R 抑制剂

AG-1024 (Tyrphostin)是胰岛素样生长因子-1 (IGF-1) 和胰岛素受体酪氨酸激酶活性的特异性抑制剂。与胰岛素受体相比，IGF-1的IC50值更低。还抑制胰岛素刺激的细胞增殖。了解更多

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- Maeda A, .et al. Safranal, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves glucose tolerance in diabetic KK-Ay mice., Mol Nutr Food Res. , 2014, 58(6):1177-89 PMID: 24668740
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NVP-ADW742

Catalog No. A10658
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IGF-1R 抑制剂

NVP-ADW742是一种IGF-1R抑制剂，IC50为0.17μM。了解更多

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- Kazuya Takayama, .et al. Leucine/glutamine and v-ATPase/lysosomal acidification via mTORC1 activation are required for position-dependent regeneration, Sci Rep, 2018, 8: 8278 PMID: 29844341
- Kentaro Hirose, .et al. Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins, BMC Dev Biol, 2014, 14: 42. PMID: 25480380
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Picropodophyllin

Catalog No. A12195
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Picropodophyllin是首个靶向口服小分子igf-1受体抑制剂，IC50为1 nM。对胰岛素受体无影响。了解更多

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PQ 401

Catalog No. A11951
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IGF-1R 抑制剂

PQ 401是可透过细胞的苯基喹啉基-脲化合物，可抑制IGF-1R自磷酸化，IC50为低于1 μM。了解更多

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Adooq Bioscience

使用 'IGF-1R' 作为标签的产品

AG-1024 (Tyrphostin)

NVP-ADW742

Picropodophyllin

PQ 401

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