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PS-1145

Catalog No. A12789
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IKK 抑制剂

PS-1145是一种高度特异性的IKB激酶（IKK）抑制剂，可有效抑制PC细胞的基础和诱导型NF-kB活性。了解更多

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BI605906

Catalog No. A13537
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IKKβ 抑制剂

BI605906是IKK beta的新型抑制剂。了解更多

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Bardoxolone methyl (RTA 402)

Catalog No. A11323
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IκB/IKK 抑制剂

Bardoxolone甲基是口服的一流的合成三萜类化合物。它是Nrf2途径的诱导剂，可以抑制氧化应激和炎症。了解更多

Product Citations (4)

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- Nakamura S, .et al. Nrf2 Activator RS9 Suppresses Pathological Ocular Angiogenesis and Hyperpermeability, Invest Ophthalmol Vis Sci, 2019, 60: 1943-1952
- Hisamichi M, .et al. Role of bardoxolone methyl, a nuclear factor erythroid 2-related factor 2 activator, in aldosterone- and salt-induced renal injury, Hypertens Res, 2018, Jan;41(1):8-17 PMID: 28978980
- Takahiko Imai, .et al. Nrf2 activator ameliorates hemorrhagic transformation in focal cerebral ischemia under anticoagulation, Neurobiol Dis, 2016, May;89:136-46 PMID: 26850917
- Takagi T, .et al. Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia-reperfusion injury., Free Radic Biol Med., 2014, 72:124-33 PMID: 24746614