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SB 203580

Catalog No. A10824
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p38 MAPK 抑制剂

SB 203580是p38α和p38β的特异性抑制剂，可抑制MAPKAP激酶2和热激蛋白27的下游激活。了解更多

Product Citations (9)

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- Lei Zhang, .et al. Ripk3 signaling regulates HSCs during stress and represses radiation-induced leukemia in mice, Stem Cell Reports, 2022, Jun 14;17(6):1428-1441 PMID: 35561683
- Tomoyuki Hashimoto, .et al. Development of radioiodinated pyrimidinopyridone derivatives as targeted imaging probes of activated p38α for single photon emission computed tomography, Ann Nucl Med, 2021, Aug 19 PMID: 34410619
- Y Zou, .et al. Autophagy inhibition enhances Matrine derivative MASM induced apoptosis in cancer cells via a mechanism involving reactive oxygen species-mediated PI3K/Akt/mTOR and Erk/p38 signaling, BMC Cancer, 2019, Oct 15;19(1):949 PMID: 31615459
- Wei P, .et al. Transforming growth factor (TGF)-β1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis, Cell Death Dis, 2019, Sep 11;10(9):670 PMID: 31511493
- Uwada J, .et al. Store-operated calcium entry (SOCE) contributes to phosphorylation of p38 MAPK and suppression of TNF-α signalling in the intestinal epithelial cells, Cell Signal, 2019, Nov;63:109358 PMID: 31295519
- Byungki Jang, .et al. The Peptidylarginine Deiminase Inhibitor Cl-Amidine Suppresses Inducible Nitric Oxide Synthase Expression in Dendritic Cells, Int J Mol Sci, 2017, Nov; 18(11): 2258 PMID: 29077055
- Uwada J, .et al. Activation of muscarinic receptors prevents TNF-α-mediated intestinal epithelial barrier disruption through p38 MAPK, Cell Signal, 2017, Jul;35:188-196 PMID: 28412413
- ZHIQIANG ZHANG, .et al. Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway., Mol Med Rep. , 2015, Jul;12(1):1499-505. PMID: 25815691
- Choe YJ, .et al. Nutlin-3 induces HO-1 expression by activating JNK in a transcription-independent manner of p53., Int J Oncol., 2014, 44(3):761-8. PMID: 24366007
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Pexmetinib (ARRY-614)

Catalog No. A10895
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p38 MAPK 抑制剂

Pexmetinib (ARRY-614)是通过双重抑制p38促分裂原活化蛋白激酶（MAPK）和Tie2/Tek受体酪氨酸激酶，其在HEK-293细胞中的IC50分别为4 nM/18 nM。Pexmetinib是一种有效的细胞因子合成抑制剂。了解更多

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BMS-582949

Catalog No. A13563
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p38 MAPK 抑制剂

BMS-582949是一种双重作用p38激酶抑制剂，非常适合于避免增加细胞p38活化的耐药机制。了解更多

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Asiatic acid

Catalog No. A10092
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Anti-inflammatory agent

Asiatic acid常用于伤口愈合。亚洲酸具有抗氧化，抗炎和神经保护的特性。积雪草酸衍生物的合成可用作抗癌剂；糖原磷酸化酶抑制剂；保肝剂。了解更多

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- Rakhi Mishra, .et al. Comparative study of High-performance thin-layer chromatography and Antioxidant potential of Hydrocotyle asiatica mother tincture used in Homoeopathy, Indian J Res Homoeopathy, 2022, Sep 27

Adooq Bioscience

使用 'p38 MAPK' 作为标签的产品

SB 203580

Pexmetinib (ARRY-614)

BMS-582949

Asiatic acid

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