订阅到源订阅

使用 'SIRT1' 作为标签的产品

Quick View
EX 527 (Selisistat)

Catalog No. A10377
Quick View

添加到收藏
SIRT1 抑制剂

EX 527 (Selisistat)是一种有效的选择性SIRT1 III类组蛋白脱乙酰基酶抑制剂，在无细胞分析中的IC50为38 nM。了解更多

Product Citations (5)

Bulk Inquiry Free Sample
- Takeshi Nakamura, .et al. Effects of NAD+ Synthesis Levels on Sirtuin 1 Deacetylase Activity in Mammalian Cells, Shimane Journal of Medical Science, 2022, 38 (2), 59-66
- Bugga Paramesha, .et al. Sirt1 and Sirt3 Activation Improved Cardiac Function of Diabetic Rats via Modulation of Mitochondrial Function, Antioxidants (Basel), 2021, Feb 24;10(3):338 PMID: 33668369
- Wenhui Yao, .et al. Icariin ameliorates endothelial dysfunction in type 1 diabetic rats by suppressing ER stress via the PPARα/Sirt1/AMPKα pathway, J Cell Physiol, 2020, 07 August
- Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48
- Yoshikawa A, .et al. Deletion of Atf6α impairs astroglial activation and enhances neuronal death following brain ischemia in mice, J Neurochem, 2015, Feb;132(3):342-53 PMID: 25351847
Quick View
SRT1720 HCl

Catalog No. A10862
Quick View

添加到收藏
SIRT1 Activator

SRT1720 HCl是一种抑制剂，旨在作为瑟土因亚型SIRT1的小分子活化剂。了解更多

Product Citations (7)

Bulk Inquiry Free Sample
- Eleni Pitsillou, .et al. Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay, Comput Biol Chem, 2020, 89: 107408 PMID: 33137690
- Jie Ren, .et al. Melatonin prevents chronic intermittent hypoxia-induced injury by inducing sirtuin 1-mediated autophagy in steatotic liver of mice, Sleep Breath, 2018, Nov 8 PMID: 30411173
- Rowlands BD, .et al. Acetate metabolism does not reflect astrocytic activity, contributes directly to GABA synthesis, and is increased by silent information regulator 1 activation, J Neurochem, 2017, Mar;140(6):903-918 PMID: 27925207
- Adam Khader, .et al. SRT1720, a sirtuin 1 activator, attenuates organ injury and inflammation in sepsis, J Surg Res, 2017, Nov;219:288-295 PMID: 29078895
- Adam Khader, .et al. Sirtuin 1 Stimulation Attenuates Ischemic Liver Injury and Enhances Mitochondrial Recovery and Autophagy, Crit Care Med, 2016, Aug; 44(8): e651-e663 PMID: 26963320
- Benjamin D. Rowlands, .et al. Silent information regulator 1 modulator resveratrol increases brain lactate production and inhibits mitochondrial metabolism, whereas SRT1720 increases oxidative metabolism., J Neurosci Res., 2015, Jul;93(7):1147-56 PMID: 25677687
- Khader A, .et al. Sirtuin 1 activation stimulates mitochondrial biogenesis and attenuates renal injury after ischemia-reperfusion., Transplantation, 2014, 98(2):148-56 PMID: 24918615
Quick View
SRT2104 (GSK2245840)

Catalog No. A14188
Quick View

添加到收藏
SIRT1 activator

SRT2104 (GSK2245840)是一种选择性sirt1激活剂，参与能量稳态的调节。了解更多

Product Citations (2)

Bulk Inquiry
- Eleni Pitsillou, .et al. Interaction of small molecules with the SARS-CoV-2 main protease in silico and in vitro validation of potential lead compounds using an enzyme-linked immunosorbent assay, Comput Biol Chem, 2020, 89: 107408 PMID: 33137690
- Liu X, .et al. Exploring the role of orexin B-sirtuin 1-HIF-1α in diabetes-mellitus induced vascular endothelial dysfunction and associated myocardial injury in rats, Life Sci, 2019, Nov 9:117041 PMID: 31715188
Quick View
Tenovin-6

Catalog No. A12305
Quick View

添加到收藏
p53 activator

Tenovin-6是tenovin-1的类似物。Tenovin-6在体外抑制纯化的人SIRT1、SIRT2和SIRT3的蛋白脱乙酰酶活性，IC50值分别为21、10和67 uM。了解更多

Product Citations (1)

Bulk Inquiry Free Sample
- Igase M,, .et al. Tenovin-6 induces the SIRT-independent cell growth suppression and blocks autophagy flux in canine hemangiosarcoma cell lines, Exp Cell Res, 2019, Dec 28:111810 PMID: 31891684

Adooq Bioscience

使用 'SIRT1' 作为标签的产品

EX 527 (Selisistat)

SRT1720 HCl

SRT2104 (GSK2245840)

Tenovin-6

JOIN OUR REWARDS PROGRAM TODAY AND START EARNING POINTS RIGHT AWAY !

Total item