TAK-438 (vonoprazan)

Name: TAK-438 (vonoprazan)
SKU: A11239

目录号: A11239

potassium-competitive acid Blocker

TAK-438 (vonoprazan) Chemical Structure

CAS NO. 1260141-27-2

TAK-438 (vonoprazan)是一种新型的钾竞争酸阻滞剂。

库存：现货

规格	价格	数量
2 mg	￥ 630.00
5 mg	￥ 1,050.00
10 mg	￥ 1,960.00
25 mg	￥ 3,640.00
10mM * 1mL in DMSO	￥ 1,869.00

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产品详情

生物活性

TAK-438 (vonoprazan)是一种新型的钾竞争酸阻滞剂。

靶点信息

H+/K+-ATPase
19 nM

溶解度 *

In vitro (25°C)	DMSO	58 mg/mL (125.68 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% methylcellulose	16 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.67 mL	108.34 mL	216.68 mL
0.5 mM	4.33 mL	21.67 mL	43.34 mL
1 mM	2.17 mL	10.83 mL	21.67 mL
5 mM	0.43 mL	2.17 mL	4.33 mL

*The above data is based on the productmolecular weight 461.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11239
作用机制	Blocker (阻断剂)
M. Wt	461.5
Formula	C21H20FN3O6S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1260141-27-2
Synonyms	TAK438
SMILES	CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O