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Talnetant Hydrochloride是一种有效且选择性的NK3受体拮抗剂（ki = 1.4 nM，hNK-3-CHO）；对hNK-3受体的选择性是对hNK-2受体的100倍，在浓度高达100 uM时对hNK-1没有亲和力。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.87 mL | 119.35 mL | 238.71 mL |
| 0.5 mM | 4.77 mL | 23.87 mL | 47.74 mL |
| 1 mM | 2.39 mL | 11.94 mL | 23.87 mL |
| 5 mM | 0.48 mL | 2.39 mL | 4.77 mL |
*The above data is based on the productmolecular weight 418.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15255 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 418.92 |
| Formula | C25H23ClN2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 204519-66-4 |
| Synonyms | SB-223412 hydrochloride, SB223412 hydrochloride, SB 223412 hydrochloride, SB 223412-A |
| SMILES | CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O.Cl |
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