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Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.38 mL | 96.91 mL | 193.82 mL |
| 0.5 mM | 3.88 mL | 19.38 mL | 38.76 mL |
| 1 mM | 1.94 mL | 9.69 mL | 19.38 mL |
| 5 mM | 0.39 mL | 1.94 mL | 3.88 mL |
*The above data is based on the productmolecular weight 515.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11578 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 515.95 |
| Formula | C27H25ClF3N3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 701977-09-5 |
| Synonyms | MK-0364 |
| SMILES | ClC1=CC=C(C[C@@H](C2=CC=CC(C#N)=C2)[C@@H](NC(C(C)(OC3=CC=C(C=N3)C(F)(F)F)C)=O)C)C=C1 |
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