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TC-E 5002是一种选择性组蛋白脱甲基酶KDM2/7亚家族抑制剂（KDM7A，KDM7B，KDM2A，KDM5A，KDM4C，KDM6A和KDM4A的IC50值分别为0.2、1.2、6.8、55、83，> 100和> 120 uM）。在体外抑制HeLa和KYSE-150癌细胞的生长。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.04 mL | 175.2 mL | 350.41 mL |
| 0.5 mM | 7.01 mL | 35.04 mL | 70.08 mL |
| 1 mM | 3.5 mL | 17.52 mL | 35.04 mL |
| 5 mM | 0.7 mL | 3.5 mL | 7.01 mL |
*The above data is based on the productmolecular weight 285.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16373 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 285.38 |
| Formula | C15H27NO4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1453071-47-0 |
| SMILES | O=C(N(O)CCC(O)=O)CCCCCCCCC1CC1 |
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