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Tenapanor充当钠-质子交换器NHE3的抑制剂。这种抗转运蛋白在肾脏和肠道中发现，通常起到调节机体吸收和分泌的钠水平的作用。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 8.73 mL | 43.67 mL | 87.33 mL |
| 0.5 mM | 1.75 mL | 8.73 mL | 17.47 mL |
| 1 mM | 0.87 mL | 4.37 mL | 8.73 mL |
| 5 mM | 0.17 mL | 0.87 mL | 1.75 mL |
*The above data is based on the productmolecular weight 1145.0614. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14011 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 1145.0614 |
| Formula | C50H66Cl4N8O10S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1234423-95-0 |
| Synonyms | AZD1722, RDX5791 |
| SMILES | CN1C[C@H](C2=CC(=CC(=C2C1)Cl)Cl)C3=CC(=CC=C3)S(=O)(=O)NCCOCCOCCNC(=O)NCCCCNC(=O)NCCOCCOCCNS(=O)(=O)C4=CC=CC(=C4)[C@@H]5CN(CC6=C(C=C(C=C56)Cl)Cl)C |
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