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TG 100801 HCl是TG 100572（HY-10184）的前药，TG 100572是一种多靶点激酶抑制剂，可抑制选择性生长因子受体酪氨酸激酶和Src家族激酶，IC50值为2/7/2/1/0.5 nM或VEGFR1/VEGFR2/FGFR1/Src/Fyn kianse分别。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.22 mL | 81.1 mL | 162.2 mL |
| 0.5 mM | 3.24 mL | 16.22 mL | 32.44 mL |
| 1 mM | 1.62 mL | 8.11 mL | 16.22 mL |
| 5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
*The above data is based on the productmolecular weight 616.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15261 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 616.54 |
| Formula | C33H31Cl2N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1018069-81-2 |
| Synonyms | TG100801 Hydrochloride, TG-100801 Hydrochloride |
| SMILES | CC1=C2C(=CC(=C1)C3=C(C=CC(=C3)OC(=O)C4=CC=CC=C4)Cl)N=NC(=N2)NC5=CC=C(C=C5)OCCN6CCCC6.Cl |
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