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Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.35 mL | 86.73 mL | 173.47 mL |
| 0.5 mM | 3.47 mL | 17.35 mL | 34.69 mL |
| 1 mM | 1.73 mL | 8.67 mL | 17.35 mL |
| 5 mM | 0.35 mL | 1.73 mL | 3.47 mL |
*The above data is based on the productmolecular weight 576.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21634 |
|---|---|
| M. Wt | 576.48 |
| Formula | C23H27F3N4O10 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1957235-75-4 |
| Synonyms | Cereblon Ligand-Linker Conjugates 10 (TFA); E3 Ligase Ligand-Linker Conjugates 24 (TFA) |
| SMILES | O=C(NCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F |
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