Ticagrelor (AZD6140)

Name: Ticagrelor (AZD6140)
SKU: A11238

目录号: A11238

P2Y12 拮抗剂

Ticagrelor (AZD6140) Chemical Structure

CAS NO. 274693-27-5

Ticagrelor (AZD6140)是第一个可逆结合的口服P2Y（12）受体拮抗剂，可阻断ADP诱导的血小板聚集。

库存：现货

规格	价格	数量
50 mg	￥ 560.00
25 mg	￥ 350.00

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生物活性

Ticagrelor (AZD6140)是第一个可逆结合的口服P2Y（12）受体拮抗剂，可阻断ADP诱导的血小板聚集。

溶解度 *

In vitro (25°C)	DMSO	99 mg/mL (189.45 mM)
	Water	Insoluble
	Ethanol	52 mg/mL (99.51 mM)
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.14 mL	95.68 mL	191.35 mL
0.5 mM	3.83 mL	19.14 mL	38.27 mL
1 mM	1.91 mL	9.57 mL	19.14 mL
5 mM	0.38 mL	1.91 mL	3.83 mL

*The above data is based on the productmolecular weight 522.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11238
作用机制	Antagonist (拮抗剂)
M. Wt	522.6
Formula	C23H28F2N6O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	274693-27-5
Synonyms	AZD 6140
SMILES	CCCSC1=NC2=C(C(=N1)N[C@@H]3C[C@H]3C4=CC(=C(C=C4)F)F)N=NN2[C@@H]5C[C@@H]([C@H]([C@H]5O)O)OCCO