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Tiplaxtinin (PAI-039)

Tiplaxtinin (PAI-039)

Name: Tiplaxtinin (PAI-039)
SKU: A14190

目录号: A14190

PAI-1 inhbitor

Product Citations (1)

Tiplaxtinin (PAI-039) Chemical Structure

CAS NO. 393105-53-8

Tiplaxtinin (PAI-039)是一种纤溶酶原激活物抑制剂1（PAI-1）的选择性口服有效抑制剂，IC50为2.7μM。

库存：现货

规格	价格	数量
5 mg	￥ 525.00
10 mg	￥ 595.00
25 mg	￥ 1,400.00

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生物活性

Tiplaxtinin (PAI-039)是一种纤溶酶原激活物抑制剂1（PAI-1）的选择性口服有效抑制剂，IC50为2.7μM。

靶点信息

PAI-1
2.7 μM

溶解度 *

In vitro (25°C)	DMSO	62 mg/mL (141.1 mM)
	Water	Insoluble
	Ethanol	Warmed: 15 mg/mL (34.13 mM)
In vivo	2.0% Tween 80+0.5% methylcellulose	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.76 mL	113.8 mL	227.59 mL
0.5 mM	4.55 mL	22.76 mL	45.52 mL
1 mM	2.28 mL	11.38 mL	22.76 mL
5 mM	0.46 mL	2.28 mL	4.55 mL

*The above data is based on the productmolecular weight 439.3833. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14190
作用机制	Inhibitor (抑制剂)
M. Wt	439.3833
Formula	C24H16F3NO4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	393105-53-8
Synonyms	PAI-039
SMILES	C1=CC=C(C=C1)CN2C=C(C3=C2C=CC(=C3)C4=CC=C(C=C4)OC(F)(F)F)C(=O)C(=O)O