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Toll-Like Receptor 7 Ligand II是一种细胞可渗透的羟基腺嘌呤化合物，可作为强效且高度特异性的TLR7（toll样受体7）激动剂，对TLR2/3/5/8/9没有任何可检测的活性。它在刺激体外培养物中产生TLR7依赖性细胞因子方面比R848效力高10倍。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.71 mL | 158.56 mL | 317.13 mL |
| 0.5 mM | 6.34 mL | 31.71 mL | 63.43 mL |
| 1 mM | 3.17 mL | 15.86 mL | 31.71 mL |
| 5 mM | 0.63 mL | 3.17 mL | 6.34 mL |
*The above data is based on the productmolecular weight 315.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12683 |
|---|---|
| M. Wt | 315.33 |
| Formula | C15H17N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 226907-52-4 |
| Synonyms | CL087; SM360320 |
| SMILES | COCCOC1=NC2=C(C(=N1)N)NC(=O)N2CC3=CC=CC=C3 |
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