Toll-like Receptors

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VGX-1027

Catalog No. A12548
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TLR4 抑制剂

VGX-1027通过抑制Toll样受体4（TLR4）信号传导来显示免疫调节和抗炎活性。了解更多

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TLR2-IN-C29

Catalog No. A17160
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TLR 抑制剂

TLR2-IN-C29是TLR2/1和TLR2/6信号传导的抑制剂。了解更多

Product Citations (1)

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- Qian-Lu Wang, .et al. ROCK1 regulates sepsis-induced acute kidney injury via TLR2-mediated endoplasmic reticulum stress/pyroptosis axis, Mol Immunol, 2021, Oct;138:99-109 PMID: 34365196
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AN-3485

Catalog No. A20989
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TLR inhibitor

AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. 了解更多

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Resatorvid

Catalog No. A11543
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TLR4 inhibitor

Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor and plays pivotal role in various inflammatory diseases. 了解更多

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MD2-TLR4-IN-1

Catalog No. A18452
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MD2-TLR4 inhibitor

MD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多

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TAK-242 S enantiomer

Catalog No. A15253
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TLR4 抑制剂

TAK-242的S对映体。TAK-242（Resatorvid），Toll样受体（TLR）4信号转导的小分子抑制剂。TAK-242用于治疗败血症和败血性休克。了解更多

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