Toll-like Receptors

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  1. AN-3485

    Catalog No. A20989
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    TLR inhibitor
    AN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. 了解更多
  2. TLR7/8 agonist 1 dihydrochloride

    Catalog No. A21700
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    TLR7/8 agonist
    TLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. 了解更多
  3. Resatorvid

    Catalog No. A11543
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    TLR4 inhibitor
    Resatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor and plays pivotal role in various inflammatory diseases. 了解更多
  4. PF-4878691

    Catalog No. A12233
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    TLR7 agonist
    PF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities. 了解更多
  5. MD2-TLR4-IN-1

    Catalog No. A18452
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    MD2-TLR4 inhibitor
    MD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. 了解更多
  6. IAXO-102

    Catalog No. A18543
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    TLR4 antagonist
    IAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. 了解更多
  7. Resiquimod

    Catalog No. A15890
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    TLR7/8 激动剂
    Resiquimod是一种免疫应答调节剂,可作为有效的TLR 7/8激动剂。阶段2。 了解更多
  8. Isatoribine

    Catalog No. A14351
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    TLR7 激动剂
    Isatoribine是一种新型的鸟苷类似物,在体内和体外均显示出免疫刺激活性。 了解更多
  9. TAK-242 S enantiomer

    Catalog No. A15253
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    TLR4 抑制剂
    TAK-242的S对映体。TAK-242(Resatorvid),Toll样受体(TLR)4信号转导的小分子抑制剂。TAK-242用于治疗败血症和败血性休克。 了解更多
  10. GS-9620

    Catalog No. A13251
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    TLR7 激动剂
    GS-9620是Toll样受体7的有效选择性口服活性小分子激动剂。 了解更多
  11. Imiquimod (Aldara)

    Catalog No. A10469
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    TLR7 激动剂
    Imiquimod (Aldara)是一种杂环咪唑并喹啉酰胺,用作免疫反应调节剂。 了解更多
  12. Toll-like receptor modulator

    Catalog No. A15264
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    Toll-like receptor modulator是一类在先天免疫系统中起关键作用的蛋白质。是一类在先天免疫系统中起关键作用的蛋白质。 了解更多
  13. Gardiquimod TFA

    Catalog No. A17050
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    TLR7 激动剂
    Gardiquimod TFA是一种化合物,可选择性作用于小鼠和人类形式的Toll样受体7(TLR7)。它起免疫反应调节剂的作用。CAS:1020412-43-4(游离碱) 了解更多
  14. TLR2-IN-C29

    Catalog No. A17160
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    TLR 抑制剂
    TLR2-IN-C29是TLR2/1和TLR2/6信号传导的抑制剂。 了解更多
  15. TLR7-agonist-1

    Catalog No. A17018
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    TLR7 激动剂
    TLR7-agonist-1是一种有效且选择性的Toll样受体7(TLR7)激动剂,LEC为0.4 μM。 了解更多
  16. Hydroxychloroquine Sulfate

    Catalog No. A14208
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    Hydroxychloroquine Sulfate是一种抗疟疾药,用于治疗系统性红斑狼疮,类风湿性关节炎和其他自身免疫性,炎性和皮肤病性疾病。还可以作为自噬和通行费样受体(TLR)7/9的抑制剂。 了解更多
  17. VGX-1027

    Catalog No. A12548
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    TLR4 抑制剂
    VGX-1027通过抑制Toll样受体4(TLR4)信号传导来显示免疫调节和抗炎活性。 了解更多
  18. VTX-2337

    Catalog No. A12841
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    TLR8 激动剂
    VTX-2337是一种具有潜在的免疫刺激和抗肿瘤活性的小分子Toll样受体8(TLR8)激动剂。 了解更多
  19. Toll-Like Receptor 7 Ligand II

    Catalog No. A12683
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    TLR7 Ligand
    Toll-Like Receptor 7 Ligand II是一种细胞可渗透的羟基腺嘌呤化合物,可作为强效且高度特异性的TLR7(toll样受体7)激动剂,对TLR2/3/5/8/9没有任何可检测的活性。它在刺激体外培养物中产生TLR7依赖性细胞因子方面比R848效力高10倍。 了解更多

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