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Tradipitant，也称为VLY-686和LY686017，是第二代神经激肽1受体拮抗剂，在临床前焦虑模型中表现出活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.01 mL | 85.05 mL | 170.1 mL |
| 0.5 mM | 3.4 mL | 17.01 mL | 34.02 mL |
| 1 mM | 1.7 mL | 8.5 mL | 17.01 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.4 mL |
*The above data is based on the productmolecular weight 587.9. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16918 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 587.9 |
| Formula | C28H16ClF6N5O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 622370-35-8 |
| Synonyms | LY-686017, LY 686017, LY686017, VLY 686, VLY686, VLY-686 |
| SMILES | O=C(C1=CC=CN=C1C2=C(C3=CC=NC=C3)N(CC4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)N=N2)C5=CC=CC=C5Cl |
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