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Tranilast是一种抗过敏药。它减少了成纤维细胞中的胶原蛋白合成，并抑制了神经纤维瘤细胞的生长，还抑制了内皮细胞中白介素6的产生。
靶点信息
| In vitro | DMSO | 57 mg/mL (174.14 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.55 mL | 152.77 mL | 305.53 mL |
| 0.5 mM | 6.11 mL | 30.55 mL | 61.11 mL |
| 1 mM | 3.06 mL | 15.28 mL | 30.55 mL |
| 5 mM | 0.61 mL | 3.06 mL | 6.11 mL |
*The above data is based on the productmolecular weight 327.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10942 |
|---|---|
| M. Wt | 327.3 |
| Formula | C18H17NO5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 53902-12-8 |
| Synonyms | SB252218 |
| SMILES | COC1=C(C=C(C=C1)/C=C/C(=O)NC2=CC=CC=C2C(=O)O)OC |
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