购物车 0 ￥ 0.00
微信关注
申请试用装
  • 主页 /
  • Membrane Transporters/Ion Channels

Membrane Transporters/Ion Channels

产品 151 到 200 共 317个

每页
页面：
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6

设置升序顺序
  1. NS-1643
    Quick View

    NS-1643

    Catalog No. A15929
    Quick View
    hERG channel activator
    NS-1643是一种人类以太相关基因（hERG）KV11.1通道激活剂（EC50 = 10.5 uM）。 了解更多
  2. NS1619
    Quick View

    NS1619

    Catalog No. A15975
    Quick View
    Potassium channel activator
    NS1619是Bkca开启剂或大电导Ca2+激活的钾（BKCa，KCa1.1）通道激活剂。 了解更多
  3. Doxapram
    Quick View

    Doxapram

    Catalog No. A15961
    Quick View
    Doxapram能抑制TASK-1，TASK-3，TASK-1/TASK-3异二聚体通道功能，EC50分别为410 nM，37μM，9μM。Doxapram是一种呼吸刺激剂。静脉注射多沙普兰可刺激潮气量和呼吸频率的增加。 了解更多
  4. K+ Channel inhibitor
    Quick View

    K+ Channel inhibitor

    Catalog No. A16182
    Quick View
    K+ Channel 抑制剂
    K+ Channel inhibitor，Kv1.5（IKur）的二氢吡唑并嘧啶抑制剂的合成基础。 了解更多
  5. Cesium chloride
    Quick View

    Cesium chloride

    Catalog No. A15341
    Quick View
    Potassium channel blocker
    Cesium chloride是钾通道阻滞剂。抑制起搏器电流（If）和超极化激活的阳离子电流（Ih）。通过灭活GSK-3β来防止血清和钾缺乏的小脑颗粒神经元中caspase-3的激活和神经元凋亡。 了解更多
  6. SKA-31
    Quick View
    • 最新产品

    SKA-31

    Catalog No. A17117
    Quick View
    potassium channel activator
    SKA-31是KCa2和KCa3.1钙激活钾通道的激活剂。 了解更多
  7. 4-Aminopyridine
    Quick View

    4-Aminopyridine

    Catalog No. A17490
    Quick View
    Potassium channel blocker
    Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. 了解更多
  8. AUT1
    Quick View

    AUT1

    Catalog No. A18648
    Quick View
    Kv3 potassium channel modulator
    AUT1 is a Kv3 potassium channel modulator with pEC50s of 5.33 and 5.31 for human recombinant Kv3.1b and Kv3.2a, respectively, exhibits 10-fold lower potency at human recombinant Kv3.3 channel (pEC50, 4.5). 了解更多
  9. ML418
    Quick View

    ML418

    Catalog No. A18426
    Quick View
    Kir7.1 potassium channels blocker
    ML418 is a selective, sub-micromolar pore blocker of Kir7.1 potassium channels. The inward rectifier potassium (Kir) channel Kir7.1 (KCNJ13) is a key regulator of melanocortin signaling in the brain, electrolyte homeostasis in the eye, and uterine muscle contractility during pregnancy. 了解更多
  10. Y-26763
    Quick View

    Y-26763

    Catalog No. A12271
    Quick View
    K+ (KATP) channel activator
    Y-26763 is a K+ channel opener and active metabolite of Y-27152. Y-26763 is an ATP-sensitive K+ (KATP) channel activator. 了解更多
  11. JNJ 303
    Quick View

    JNJ 303

    Catalog No. A20952
    Quick View
    IKs blocker
    JNJ 303 is a potent IKs blocker with an IC50 value of 64 nM. 了解更多
  12. RPR-260243
    Quick View

    RPR-260243

    Catalog No. A20977
    Quick View
    HERG activator
    RPR-260243 is a novel activator of HERG; modifies HERG currents inhibited by dofetilide (IC50 = 58 nM); little effect on HERG current amplitude and no significant effects on steady-state activation parameters or on channel inactivation processes. 了解更多
  13. MK-7145
    Quick View

    MK-7145

    Catalog No. A21030
    Quick View
    ROMK inhibitor
    MK-7145 is a ROMK inhibitor, with an IC50 of 0.045 μM. 了解更多
  14. Ivermectin
    Quick View

    Ivermectin

    Catalog No. A10490
    Quick View
    Ivermectin是一种广谱抗寄生虫阿维菌素药物。 了解更多
  15. Talniflumate
    Quick View

    Talniflumate

    Catalog No. A13339
    Quick View
    CaCC blocker
    Talniflumate是一种钙激活的氯离子通道（CaCC）（hCLCA1/mCLCA3）阻滞剂；在细胞培养和动物模型中减少粘蛋白的合成和释放。 了解更多
  16. CaCCinh-A01
    Quick View

    CaCCinh-A01

    Catalog No. A15469
    Quick View
    CaCCs 抑制剂
    CaCCinh-A01抑制人支气管和肠道细胞中的CaCC电流。还抑制TMEM16A通道（表达TMEM16A的FRT细胞中IC50 = 2.1 uM）。 了解更多
  17. T16Ainh-A01
    Quick View

    T16Ainh-A01

    Catalog No. A15470
    Quick View
    TMEM16A 抑制剂
    T16Ainh-A01是一种选择性TMEM16A钙激活的氯离子通道抑制剂，可强烈抑制唾液腺细胞中的氯离子电流。 了解更多
  18. Eact
    Quick View

    Eact

    Catalog No. A16179
    Quick View
    CaCC activator
    Eact激活钙激活的氯离子通道（CaCC）TMEM16A CaCC。 了解更多
  19. NPPB
    Quick View

    NPPB

    Catalog No. A16981
    Quick View
    chloride channel blocker
    NPPB是一种氯离子通道阻滞剂（IC50 = 80 nM），也被确定为GPR35激动剂。 了解更多
  20. Dapagliflozin (BMS512148)
    Quick View

    Dapagliflozin (BMS512148)

    Catalog No. A10285
    Quick View
    SGLT2 抑制剂
    Dapagliflozin (BMS512148)抑制钠-葡萄糖转运蛋白（SGLT2）的亚型2，后者负责肾脏中至少90％的葡萄糖重吸收。 了解更多
  21. Canagliflozin
    Quick View

    Canagliflozin

    Catalog No. A11100
    Quick View
    SGLT2 抑制剂
    canagliflozin是2型亚钠葡萄糖转运蛋白（SGLT2）的抑制剂,作用于hSGLT2，无细胞试验中IC50为2.2 nM，比作用于hSGLT1选择性高413倍。 了解更多
  22. EGT1442
    Quick View

    EGT1442

    Catalog No. A10155
    Quick View
    SGLT2 抑制剂
    EGT1442是有效的选择性SGLT2抑制剂。 了解更多
  23. Empagliflozin
    Quick View

    Empagliflozin

    Catalog No. A12440
    Quick View
    Empagliflozin是一种有效的选择性葡萄糖钠共转运蛋白-2抑制剂，目前正在开发中，用于治疗2型糖尿病。 了解更多
  24. LX-4211
    Quick View

    LX-4211

    Catalog No. A12680
    Quick View
    SGLT 抑制剂?
    LX4211是双重SGLT1/SGLT2抑制剂。 了解更多
  25. Tofogliflozin
    Quick View

    Tofogliflozin

    Catalog No. A12690
    Quick View
    SGLT2 抑制剂
    Tofogliflozin是亚型2钠葡萄糖转运蛋白（SGLT2）的抑制剂，可引起肾脏中至少90％的葡萄糖重吸收。 了解更多
  26. Remogliflozin
    Quick View

    Remogliflozin

    Catalog No. A13971
    Quick View
    SGLT2 抑制剂
    Remogliflozin抑制钠葡萄糖转运蛋白（SGLT2），后者负责肾脏中的葡萄糖重吸收。 了解更多
  27. Ipragliflozin
    Quick View

    Ipragliflozin

    Catalog No. A13556
    Quick View
    SGLT2 抑制剂
    Ipragliflozin是一种高效的选择性SGLT2抑制剂，IC50为2.8 nM。SGLT1/3/4/5/6的效力很小且没有效力。 了解更多
  28. Luseogliflozin
    Quick View

    Luseogliflozin

    Catalog No. A13476
    Quick View
    SGLT2 抑制剂
    Luseogliflozin是由Taisho Pharmaceutical开发的一种口服活性第二代钠葡萄糖共转运蛋白2（SGLT2）抑制剂，用于治疗2型糖尿病（T2DM）患者。 了解更多
  29. T-1095
    Quick View

    T-1095

    Catalog No. A15463
    Quick View
    Na+-glucose transporter 抑制剂
    T-1095是Na+-葡萄糖共转运蛋白（SGLTs）的有效和选择性抑制剂。 了解更多
  30. Canagliflozin hemihydrate
    Quick View

    Canagliflozin hemihydrate

    Catalog No. A16817
    Quick View
    SGLT2 抑制剂
    Canagliflozin hemihydrate是半水形式的卡格列嗪，是一种SGLT2抑制剂，在无细胞检测中hSGLT2的IC50为2.2 nM，其选择性比hSGLT1高413倍。 了解更多
  31. Ertugliflozin L-pyroglutamic acid
    Quick View

    Ertugliflozin L-pyroglutamic acid

    Catalog No. A18054
    Quick View
    SGLT inhibitor
    Ertugliflozin pidolate belongs to the class of potent and selective inhibitors of the sodium-dependent glucose cotransporters (SGLT), more specifically the type 2 which is responsible for about 90% of the glucose reabsorption from glomerulus. 了解更多
  32. SGL5213
    Quick View

    SGL5213

    Catalog No. A18723
    Quick View
    SGLT1 抑制剂
    SGL5213 is a potent, oral active and low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor, with IC50 values of 29 nM and 20 nM for hSGLT1 and hSGLT2, respectively. 了解更多
  33. Dapagliflozin impurity
    Quick View

    Dapagliflozin impurity

    Catalog No. A19103
    Quick View
    SGLT2 抑制剂
    Dapagliflozin impurity is an enantiomer of Dapagliflozin which is a sodium-glucose transporter 2 inhibitor. 了解更多
  34. Licogliflozin
    Quick View

    Licogliflozin

    Catalog No. A12828
    Quick View
    SGLT1/SGLT2 抑制剂
    Licogliflozin is a sodium glucose cotransporter (SGLT1 and SGLT2) inhibitor. 了解更多
  35. BAY-8002
    Quick View

    BAY-8002

    Catalog No. A18611
    Quick View
    MCT1 inhibitor
    BAY-8002 is a potent, selective, orally active inhibitor of monocarboxylate transporter 1 (MCT1), with an IC50 of 85 nM in the MCT1-expressing DLD-1 cells, displays excellent selectivity against MCT4. Anti-tumor activity. 了解更多
  36. AR-C155858
    Quick View

    AR-C155858

    Catalog No. A11293
    Quick View
    MCT1 and MCT2 抑制剂
    AR-C155858是单羧酸转运蛋白mct1和mct2的有效抑制剂，它们与涉及跨膜螺旋7-10的细胞内位点结合。 了解更多
  37. CHC
    Quick View

    CHC

    Catalog No. A13372
    Quick View
    MCT 抑制剂
    CHC是单羧酸转运（MCT）抑制剂。在神经胶质瘤中具有抗肿瘤和抗血管生成活性；降低U251细胞的糖酵解代谢，迁移和侵袭。 了解更多
  38. AZD-3965
    Quick View

    AZD-3965

    Catalog No. A14186
    Quick View
    MCT1 抑制剂
    AZD-3965（AZD3965）是具有1.6 nM结合亲和力的单羧酸盐转运蛋白1（MCT1）的选择性抑制剂，是MCT2的6倍选择性，在10μM时不抑制MCT4。 了解更多
  39. AR-C117977
    Quick View

    AR-C117977

    Catalog No. A14360
    Quick View
    MCT1 抑制剂
    AR-C117977是一种有效的MCT1抑制剂，可以降低体内和体外的免疫应答，维持长期移植物存活，并诱导操作耐受性。 了解更多
  40. 7ACC2
    Quick View

    7ACC2

    Catalog No. A15785
    Quick View
    MCT 抑制剂
    7ACC2是一种新型有效的MCT抑制剂，IC50为11 nM，可抑制[14C]-乳酸盐涌入。针对癌细胞中乳酸转运的新型抗肿瘤治疗。 了解更多
  41. 7ACC1
    Quick View

    7ACC1

    Catalog No. A15810
    Quick View
    MCT 抑制剂?
    7ACC1在富含乳酸的肿瘤微环境中选择性干扰乳酸通量；在表达MCT1和MCT4转运蛋白的肿瘤细胞中，乳酸抑制乳酸盐流入，但不流出。 了解更多
  42. UK 5099
    Quick View

    UK 5099

    Catalog No. A13038
    Quick View
    MCT 抑制剂
    UK 5099是质膜单羧酸盐转运蛋白（MCT）和线粒体丙酮酸载体（MPC）的有效抑制剂。抑制丙酮酸依赖性的氧气消耗，IC50为50 nM。 了解更多
  43. Tezampanel
    Quick View

    Tezampanel

    Catalog No. A15259
    Quick View
    AMPA 拮抗剂
    Tezampanel是AMPA和离子型谷氨酸受体的海藻酸盐家族的拮抗剂，对海藻酸盐受体的GluR5亚型具有选择性。 了解更多
  44. YM90K hydrochloride
    Quick View

    YM90K hydrochloride

    Catalog No. A15495
    Quick View
    AMPA 拮抗剂
    YM90K hydrochloride是一种选择性AMPA受体拮抗剂，在局部缺血后给药后，可延迟整体缺血模型中的神经元死亡和局部缺血模型中的脑梗塞。 了解更多
  45. Talampanel
    Quick View

    Talampanel

    Catalog No. A15515
    Quick View
    AMPA/kainate receptor 拮抗剂
    Talampanel是AMPA受体的非竞争性拮抗剂，具有抗癫痫活性。 了解更多
  46. CP 465022 hydrochloride
    Quick View

    CP 465022 hydrochloride

    Catalog No. A13321
    Quick View
    AMPA 拮抗剂
    CP 465022 hydrochloride是一种选择性的非竞争性AMPA拮抗剂，在大鼠皮质神经元中的IC50为25 nM，显示出有效的抗惊厥活性。 了解更多
  47. JNJ-61432059
    Quick View

    JNJ-61432059

    Catalog No. A20209
    Quick View
    AMPAR negative modulator
    JNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. 了解更多
  48. SYM2206
    Quick View

    SYM2206

    Catalog No. A20843
    Quick View
    AMPA receptor antagonist
    SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. 了解更多
  49. PF-4778574
    Quick View

    PF-4778574

    Catalog No. A21157
    Quick View
    AMPA receptor positive allosteric modulator
    PF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models. 了解更多
  50. Fanapanel
    Quick View

    Fanapanel

    Catalog No. A21200
    Quick View
    AMPA/kainate antagonist
    Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. 了解更多

产品 151 到 200 共 317个

每页
页面：
  2. 2
  3. 3
  4. 4
  5. 5
  6. 6

设置升序顺序
FILTER BY:

购物选项

分类
  1. ATPase (22)
  2. CFTR (16)
  3. Calcium Channels (47)
  4. Sodium Channels (44)
  5. Potassium Channels (38)
  6. Chloride Channels (7)
  7. SGLT (15)
  8. Monocarboxylate transporters (MCT) (8)
  9. AMPA receptor (33)
  10. P-gp (19)
  11. CRM1 (6)
  12. TRP Channel (23)
  13. TRPV (15)
  14. Glutamate (EAAT) Transporters (1)
  15. Serotonin Transporter (3)
  16. Proton Pump (7)
  17. OCT (4)
  18. NCX (5)
  19. BCRP (6)
  20. MRP (1)
  21. Na+/H+ Exchanger (4)
  22. Monoamine Transporter (3)
作用机制
  1. Inhibitor (抑制剂) (122)
  2. Agonist (激动剂) (12)
  3. Antagonist (拮抗剂) (36)
  4. Activator (激活剂) (22)
  5. Modulator (调节剂) (15)
  6. Blocker (阻断剂) (47)
  7. Inducer (诱导剂) (3)
  8. Potentiator (增强剂) (5)
靶点
  1. DNMT (1)
溶液配制计算器

分子量计算器

稀释计算器

摩尔浓度计算器

ADOOQ 产品质量保证
Guaranteed product quality, 365 days Unconditional Return & Replacement

We promise all products to perform as described.

立即申请
Get Code
联系我们
查看FAQs

Adooq 公司

产品订购

技术资源

地址

© 2006-2019 AdooQ BioScience （南京百鑫德诺生物科技有限公司）. All Rights Reserved.
苏ICP备14027875号
Accept Payment
Rewards