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Treprostinil是前列环素的稳定类似物， 是高效的DP1和EP2激动剂，其EC50值分别为0.6±0.1和6.2±1.2 nM。在临床上用于治疗PPH。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.61 mL | 128.04 mL | 256.08 mL |
| 0.5 mM | 5.12 mL | 25.61 mL | 51.22 mL |
| 1 mM | 2.56 mL | 12.8 mL | 25.61 mL |
| 5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13719 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 390.5 |
| Formula | C23H34O5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 81846-19-7 |
| SMILES | CCCCC[C@@H](CC[C@H]1[C@@H](C[C@H]2[C@@H]1CC3=C(C2)C(=CC=C3)OCC(=O)O)O)O |
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