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TRV130 HCl (Oliceridine)是一种新型的μ-opioid 受体（MOR）G蛋白偏向配体。诱导强大的G蛋白信号传导（pEC50 = 8.1），效力和功效与吗啡相似，但β-arrestin募集和受体内在化作用要低得多。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.64 mL | 118.2 mL | 236.4 mL |
| 0.5 mM | 4.73 mL | 23.64 mL | 47.28 mL |
| 1 mM | 2.36 mL | 11.82 mL | 23.64 mL |
| 5 mM | 0.47 mL | 2.36 mL | 4.73 mL |
*The above data is based on the productmolecular weight 423.01. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15444 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 423.01 |
| Formula | C22H31ClN2O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1401031-39-7 |
| Synonyms | TRV-130, TRV 130 |
| SMILES | COC1=C(SC=C1)CNCCC2(CCOC3(C2)CCCC3)C4=CC=CC=N4.Cl |
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