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TZ9是Rad6泛素结合酶（E2酶）的新型抑制剂。抑制MDA-MB-231细胞增殖，IC50约为6 uM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.3 mL | 136.49 mL | 272.98 mL |
| 0.5 mM | 5.46 mL | 27.3 mL | 54.6 mL |
| 1 mM | 2.73 mL | 13.65 mL | 27.3 mL |
| 5 mM | 0.55 mL | 2.73 mL | 5.46 mL |
*The above data is based on the productmolecular weight 366.33. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12811 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 366.33 |
| Formula | C17H14N6O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1002789-86-7 |
| Synonyms | TZ-9, TZ 9 |
| SMILES | O=C(C1=CC=C([N+]([O-])=O)C=C1)OCC2=NC(N)=NC(NC3=CC=CC=C3)=N2 |
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