U-104

Name: U-104
SKU: A14959

目录号: A14959

Carbonic anhydrase (CA) 抑制剂

U-104 Chemical Structure

CAS NO. 178606-66-1

U-104是碳酸酐酶IX（CAIX）的新型脲基磺酰胺抑制剂。

库存：现货

规格	价格	数量
10 mg	￥ 315.00
25 mg	￥ 665.00
50 mg	￥ 1,225.00

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生物活性

U-104是碳酸酐酶IX（CAIX）的新型脲基磺酰胺抑制剂。

靶点信息

CAXII	CAIX	CAI	CAII
4.5 nM(Ki)	45.1 nM(Ki)	5.08 μM(Ki)	9.64 μM(Ki)

溶解度 *

In vitro (25°C)	DMSO	60 mg/mL (193.96 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	32.33 mL	161.64 mL	323.29 mL
0.5 mM	6.47 mL	32.33 mL	64.66 mL
1 mM	3.23 mL	16.16 mL	32.33 mL
5 mM	0.65 mL	3.23 mL	6.47 mL

*The above data is based on the productmolecular weight 309.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A14959
作用机制	Inhibitor (抑制剂)
M. Wt	309.32
Formula	C13H12FN3O3S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	178606-66-1
Synonyms	NSC 213841, U 104, U104
SMILES	C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)S(=O)(=O)N)F