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UNC0638是赖氨酸甲基转移酶g9a(ic50<15 nm)和glp(ic50=19 nm)的抑制剂，在广泛的表观遗传和非表观遗传靶标上具有优异的效力和选择性。
| In vitro | DMSO | 87 mg/mL (170.68 mM) | |
| Water | 5 mg/mL (9.81 mM) | ||
| Ethanol | 87 mg/mL (170.68 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.62 mL | 98.09 mL | 196.19 mL |
| 0.5 mM | 3.92 mL | 19.62 mL | 39.24 mL |
| 1 mM | 1.96 mL | 9.81 mL | 19.62 mL |
| 5 mM | 0.39 mL | 1.96 mL | 3.92 mL |
*The above data is based on the productmolecular weight 509.72. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12947 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 509.72 |
| Formula | C30H47N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1255580-76-7 |
| Synonyms | UNC 0638, UNC-0638 |
| SMILES | CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5 |
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