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Vilanterol trifenatate是一种长效的β-2激动剂药物，于2013年5月与葛兰素氟替卡松合用，获葛兰素史克（Brax Elmitta）出售为Breo Ellipta，用于治疗慢性阻塞性肺疾病（COPD）。
| In vitro | DMSO | 86 mg/mL (111 mM) | |
| Water | Insoluble | ||
| Ethanol | 12 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.56 mL | 102.79 mL | 205.58 mL |
| 0.5 mM | 4.11 mL | 20.56 mL | 41.12 mL |
| 1 mM | 2.06 mL | 10.28 mL | 20.56 mL |
| 5 mM | 0.41 mL | 2.06 mL | 4.11 mL |
*The above data is based on the productmolecular weight 486.43. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15998 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 486.43 |
| Formula | C24H33Cl2NO5 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 503070-58-4 |
| Synonyms | GW642444, GW-642444, GW 642444X |
| SMILES | C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)C(=O)O.C1=CC(=C(C(=C1)Cl)COCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O)Cl |
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