Vorapaxar (SCH 530348)

Name: Vorapaxar (SCH 530348)
SKU: A12832

目录号: A12832

PAR-1 拮抗剂

Product Citations (6)

Vorapaxar (SCH 530348) Chemical Structure

CAS NO. 618385-01-6

Vorapaxar (SCH 530348)是一种有效的口服活性凝血酶受体（PAR-1）拮抗剂，Ki为8.1 nM。

库存：现货

规格	价格	数量
5 mg	￥ 910.00
10 mg	￥ 1,610.00
25 mg	￥ 3,220.00
50 mg	￥ 4,760.00

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生物活性

Vorapaxar (SCH 530348)是一种有效的口服活性凝血酶受体（PAR-1）拮抗剂，Ki为8.1 nM。

靶点信息

PAR-1
8.1 nM(Ki)

溶解度 *

In vitro	DMSO	96 mg/mL (194.89 mM)
	Water	Insoluble
	Ethanol	96 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.3 mL	101.51 mL	203.01 mL
0.5 mM	4.06 mL	20.3 mL	40.6 mL
1 mM	2.03 mL	10.15 mL	20.3 mL
5 mM	0.41 mL	2.03 mL	4.06 mL

*The above data is based on the productmolecular weight 492.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12832
作用机制	Antagonist (拮抗剂)
M. Wt	492.58
Formula	C29H33FN2O4
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	618385-01-6
Synonyms	SCH530348, SCH-530348, MK-5348, MK5348, MK 5348
SMILES	CCOC(=O)N[C@@H]1CC[C@@H]2[C@@H](C1)C[C@@H]3[C@H]([C@H]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[C@H](OC3=O)C