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WR99210 is a effective inhibitor of dihydrofolate reductase (DHFR) with an IC50 of <0.075 nM. WR99210 is effective against the most pyrimethamine-resistant Plasmodium falciparum strains.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.34 mL | 126.68 mL | 253.37 mL |
| 0.5 mM | 5.07 mL | 25.34 mL | 50.67 mL |
| 1 mM | 2.53 mL | 12.67 mL | 25.34 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.07 mL |
*The above data is based on the productmolecular weight 394.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18837 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 394.68 |
| Formula | C14H18Cl3N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 47326-86-3 |
| Synonyms | WR 99210, WR-99210 |
| SMILES | CC1(N=C(N=C(N1OCCCOC2=C(C=C(C(Cl)=C2)Cl)Cl)N)N)C |
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