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XRP44X是Ras-Net（Elk-3）途径抑制剂（IC50 = 10-20 nM）。间接抑制Erk1/2激活上游的净磷酸化。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.26 mL | 131.28 mL | 262.56 mL |
| 0.5 mM | 5.25 mL | 26.26 mL | 52.51 mL |
| 1 mM | 2.63 mL | 13.13 mL | 26.26 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.25 mL |
*The above data is based on the productmolecular weight 380.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16049 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 380.87 |
| Formula | C21H21ClN4O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 729605-21-4 |
| Synonyms | XRP 44X |
| SMILES | ClC1=CC(N2CCN(C(C3=CC(C)=NN3C4=CC=CC=C4)=O)CC2)=CC=C1 |
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