产品详情
ZM-241385是一种强效且高度选择性的腺苷A2A-R拮抗剂,在心脏血管中腺苷A2A-R的pA2为9.02,相对于腺苷A1-R,腺苷A2B-R和腺苷A3-的选择性分别为1000、91和500,000。 R个站点,分别。
靶点信息
adenosine A2A receptor | ||||
In vitro | DMSO | 62 mg/mL (183.79 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 29.64 mL | 148.22 mL | 296.44 mL |
0.5 mM | 5.93 mL | 29.64 mL | 59.29 mL |
1 mM | 2.96 mL | 14.82 mL | 29.64 mL |
5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
*The above data is based on the productmolecular weight 337.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13517 |
---|---|
作用机制 | Antagonist (拮抗剂) |
M. Wt | 337.34 |
Formula | C16H15N7O2 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 139180-30-6 |
Synonyms | ZM241385, ZM 241385 |
SMILES | C1=COC(=C1)C2=NN3C(=NC(=NC3=N2)NCCC4=CC=C(C=C4)O)N |
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