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Zoledronic acid, 破骨细胞抑制剂，通过抑制甲羟戊酸途径诱导破骨细胞凋亡。
靶点信息
| Rho (Cell-free assay) | ||||
| In vitro | DMSO | <1 mg/mL | |
| Water | Insoluble | ||
| Ethanol | 0.1M NaOH (aq): 36 mg/mL (132.31 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.75 mL | 183.76 mL | 367.51 mL |
| 0.5 mM | 7.35 mL | 36.75 mL | 73.5 mL |
| 1 mM | 3.68 mL | 18.38 mL | 36.75 mL |
| 5 mM | 0.74 mL | 3.68 mL | 7.35 mL |
*The above data is based on the productmolecular weight 272.1 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11010 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 272.1 |
| Formula | C5H10N2O7P2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 118072-93-8 |
| Synonyms | Zometa, Zomera, Aclasta and Reclast |
| SMILES | C1=CN(C=N1)CC(O)(P(=O)(O)O)P(=O)(O)O |
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