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12-O-tetradecanoyl phorbol-13-acetate是佛波醇的二酯,是从巴豆油中提取的促肿瘤化合物。它是在体内和体外以nM浓度可逆的高效蛋白激酶C(PKC)激活剂。
In vitro | DMSO | 94 mg/mL (152.38 mM) | |
Water | Insoluble | ||
Ethanol | 94 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.21 mL | 81.06 mL | 162.12 mL |
0.5 mM | 3.24 mL | 16.21 mL | 32.42 mL |
1 mM | 1.62 mL | 8.11 mL | 16.21 mL |
5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
*The above data is based on the productmolecular weight 616.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A14616 |
---|---|
作用机制 | Activator (激活剂) |
M. Wt | 616.83 |
Formula | C36H56O8 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 16561-29-8 |
Synonyms | TPA, Phorbol 12-myristate 13-acetate |
SMILES | CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C |
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