目录号: A16965
Rac1 inhibitor
1A-116 是一种特定的 Rac1 抑制剂,能够阻止 EGF 引起的 Rac1 激活并阻断 Rac1-P-Rex1 之间的相互作用。1A-116 能够以浓度依赖的方式诱导凋亡并抑制细胞增殖、迁移和周期进程。1A-116 在体内还展示了高度的 抗转移活性。
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生物活性
Discription | 1A-116 is a specific Rac1 inhibitor, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo. |
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产品信息
目录号 | A16965 |
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分子式 | C16H16F3N3 |
分子量 | 307.32 |
CAS号 | 1430208-73-3 |
SMILES | N=C(NC1=CC=CC=C1C(F)(F)F)NC2=CC(C)=CC(C)=C2 |
其他名称 | 1A116, 1A 116 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 1A-116 | 1A-116 供应商 | 1A-116 花费 | 1A-116 生产商 | 订购 1A-116 | 1A-116 代理商
| 购买 1430208-73-3 | 1430208-73-3 供应商 | 1430208-73-3 花费 | 1430208-73-3 生产商 | 订购 1430208-73-3 | 1430208-73-3 代理商