1A-116

目录号: A16965
Rac1 inhibitor
1A-116 是一种特定的 Rac1 抑制剂,能够阻止 EGF 引起的 Rac1 激活并阻断 Rac1-P-Rex1 之间的相互作用。1A-116 能够以浓度依赖的方式诱导凋亡并抑制细胞增殖、迁移和周期进程。1A-116 在体内还展示了高度的 抗转移活性
Grouped product items
规格 价格 库存 数量
1mg
¥280.00
现货
5mg
¥735.00
现货
10mg
¥1,120.00
现货
25mg
¥2,030.00
现货
50mg
¥3,220.00
现货
100mg
¥4,760.00
现货
200mg
¥6,755.00
现货
10mM * 1mL in DMSO
¥840.00
现货
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生物活性
Discription

1A-116 is a specific Rac1 inhibitor, can prevent EGF-induced Rac1 activation and block Rac1-P-Rex1 interaction. 1A-116 can induce apoptosis and inhibit cell proliferation, migration and cycle progression in a concentration-dependent manner. 1A-116 also demonstrates a high antimetastatic activity in vivo.

产品信息
目录号 A16965
分子式 C16H16F3N3
分子量 307.32
CAS号 1430208-73-3
SMILES N=C(NC1=CC=CC=C1C(F)(F)F)NC2=CC(C)=CC(C)=C2
其他名称 1A116, 1A 116
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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