2,4-Diamino-6-hydroxypyrimidine

Name: 2,4-Diamino-6-hydroxypyrimidine
SKU: A13500
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A13500

GTP cyclohydrolase I inhibitor

2,4-二氨基-6-羟基嘧啶是一种特异性的GTP环化水解酶I抑制剂（新生蝶呤合成中的限速酶），阻断BH4合成并抑制NO产生。

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规格	价格	库存
100mg	¥245.00	现货
500mg	¥910.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription	2,4-Diamino-6-hydroxypyrimidine is a specific GTP cyclohydrolase I inhibitor (the rate-limiting enzyme in de novo pterin synthesis), blocks BH4 synthesis and suppresses NO production.

产品信息

目录号	A13500
分子式	C4H6N4O
分子量	126.12
CAS号	CAS: 56-06-4
SMILES	O=C1N=C(N)NC(N)=C1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	21 mg/mL (166.5 mM)
	Water	5 mg/mL (39.64 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	79.29 mL	396.45 mL	792.9 mL
0.5 mM	15.86 mL	79.29 mL	158.58 mL
1 mM	7.93 mL	39.64 mL	79.29 mL
5 mM	1.59 mL	7.93 mL	15.86 mL

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