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20(S)-Hydroxycholesterol

目录号: A21850

Smo allosteric activator

20(S)-Hydroxycholesterol

20(S)-Hydroxycholesterol Chemical Structure

CAS NO. 516-72-3

20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.

库存： 现货

规格 价格 数量
5 mg
￥ 1,323.00
10 mg
￥ 2,282.00
50 mg
￥ 6,762.00
100 mg
￥ 13,524.00
或
Warning 产品仅用于科学研究，不针对患者销售，望谅解.
产品详情

生物活性

20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.

制备储备液

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.84 mL 124.18 mL 248.35 mL
0.5 mM 4.97 mL 24.84 mL 49.67 mL
1 mM 2.48 mL 12.42 mL 24.84 mL
5 mM 0.5 mL 2.48 mL 4.97 mL

*The above data is based on the productmolecular weight 402.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号 A21850
作用机制 Activator (激活剂)
M. Wt 402.65
Formula C27H46O2
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No. 516-72-3
Synonyms 20α-Hydroxycholesterol
SMILES C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1

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