20(S)-Hydroxycholesterol

Name: 20(S)-Hydroxycholesterol
SKU: A21850
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A21850

Smo allosteric activator

20(S)-羟基胆固醇（20α-羟基胆固醇）是肿瘤蛋白平滑化蛋白（Smo）的一种变构激活剂，能够激活刺猬（Hh）信号通路，在使用NIH3T3细胞的基因转录报告检测中，其EC50为3μM。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥490.00	现货
10mg	¥840.00	现货
25mg	¥1,890.00	现货
50mg	¥3,150.00	现货
100mg	¥4,655.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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Data Sheet

SDS

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生物活性

Discription

20(S)-hydroxyCholesterol (20α-Hydroxycholesterol) is an allosteric activator of the oncoprotein smoothened (Smo) that activates the hedgehog (Hh) signaling pathway with an EC50 of 3 μM in a gene transcription reporter assay using NIH3T3 cells.

Targets

Target	Value

产品信息

目录号	A21850
分子式	C27H46O2
分子量	402.65
CAS号	516-72-3
SMILES	C[C@@]1([C@@]2([H])[C@@](C)(O)CCCC(C)C)[C@](CC2)([H])[C@@](CC=C3[C@@]4(CC[C@H](O)C3)C)([H])[C@]4([H])CC1
其他名称	20α-Hydroxycholesterol
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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