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3-Aminobenzamide是一种新型PARP抑制剂,已知它通过抑制DNA损伤的修复使细胞在体外对辐射敏感。
靶点信息
PARP | ||||
<50 nM |
In vitro (25°C) | DMSO | 26 mg/mL (190.97 mM) | |
Water | Insoluble | ||
Ethanol | 26 mg/mL | ||
In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 73.42 mL | 367.11 mL | 734.21 mL |
0.5 mM | 14.68 mL | 73.42 mL | 146.84 mL |
1 mM | 7.34 mL | 36.71 mL | 73.42 mL |
5 mM | 1.47 mL | 7.34 mL | 14.68 mL |
*The above data is based on the productmolecular weight 136.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10475 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 136.2 |
Formula | C7H8N2O |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 3544-24-9 |
Synonyms | 3-Aminobenzamide, 3-AB |
SMILES | C1=CC(=CC(=C1)N)C(=O)N |
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