产品详情
4-Methylumbelliferone是透明质酸(HA)合成的选择性抑制剂,IC50为0.4 mM。被认为可通过消耗HA合成的常用底物UDP-葡萄糖醛酸来起抑制剂的作用。
靶点信息
In vitro | DMSO | 30 mg/mL (170.29 mM) | |
Water | Insoluble | ||
Ethanol | 30 mg/mL (170.29 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 56.75 mL | 283.77 mL | 567.54 mL |
0.5 mM | 11.35 mL | 56.75 mL | 113.51 mL |
1 mM | 5.68 mL | 28.38 mL | 56.75 mL |
5 mM | 1.14 mL | 5.68 mL | 11.35 mL |
*The above data is based on the productmolecular weight 176.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A10015 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 176.2 |
Formula | C10H8O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 90-33-5 |
Synonyms | 4-MU |
SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)O |
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