5-Iodo-indirubin-3'-monoxime
目录号: A19479
GSK-3β, CDK5/P25 and CDK1/cyclin B 抑制剂
5-碘吲哚红-3'-单肟是一种强效的 GSK-3β、CDK5/P25 和 CDK1/cyclin B 抑制剂,与ATP竞争结合到激酶的催化位点,其IC50分别为9纳摩尔、20纳摩尔和25纳摩尔。
Discription | 5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively. | |||||
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Cell Research |
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目录号 | A19479 |
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分子式 | C16H10IN3O2 |
分子量 | 403.17 |
CAS号 | 331467-03-9 |
SMILES | O/N=C(C1=CC=CC=C1N2)/C2=C3C(NC4=C/3C=C(I)C=C4)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2