5-Iodo-indirubin-3'-monoxime

Name: 5-Iodo-indirubin-3'-monoxime
SKU: A19479
Price: 2030 CNY
Rating: 5 (288 reviews)

目录号: A19479

GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor

5-碘吲哚红-3'-单肟是一种强效的 GSK-3β、CDK5/P25 和 CDK1/cyclin B 抑制剂，与ATP竞争结合到激酶的催化位点，其IC50分别为9纳摩尔、20纳摩尔和25纳摩尔。

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Grouped product items
规格	价格	库存
5mg	¥2,030.00	现货
10mg	¥3,465.00	现货
25mg	¥6,860.00	现货
50mg	¥9,135.00	现货
100mg	¥12,985.00	现货
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Data Sheet

SDS

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生物活性

Discription

5-Iodo-indirubin-3'-monoxime is a potent GSK-3β, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19479
分子式	C16H10IN3O2
分子量	403.17
CAS号	331467-03-9
SMILES	O/N=C(C1=CC=CC=C1N2)/C2=C3C(NC4=C/3C=C(I)C=C4)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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