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6-Diazo-5-oxo-L-norleucine 是一种从链霉菌中分离出来的抗生素,一种 glutaminase 的拮抗剂对cKGA(肾脏型谷氨酰胺酶)的IC50值约为1 mM。
In vitro | DMSO | Insoluble | |
Water | 25 mg/mL (146.07 mM; Need ultrasonic) | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 58.43 mL | 292.14 mL | 584.28 mL |
0.5 mM | 11.69 mL | 58.43 mL | 116.86 mL |
1 mM | 5.84 mL | 29.21 mL | 58.43 mL |
5 mM | 1.17 mL | 5.84 mL | 11.69 mL |
*The above data is based on the productmolecular weight 171.15. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A20846 |
---|---|
M. Wt | 171.15 |
Formula | C6H9N3O3 |
CAS No. | 157-03-9 |
Synonyms | Diazooxonorleucine; 6-Diazo-5-oxo-L-nor-Leucine; L-6-Diazo-5-oxonorleucine; DON |
SMILES | C(CC(=O)C=[N+]=[N-])C(C(=O)O)N |
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