6-Diazo-5-oxo-L-norleucine (DON)
目录号: A20846
6-二氮杂-5-酮-L-去亮氨酸是一种谷氨酰胺拮抗剂，显示出良好的抗癌活性（特别是在胰腺癌中），并减少肿瘤细胞的自我更新潜力和转移能力。
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生物活性
| Discription | 6-Diazo-5-oxo-L-nor-Leucine is a glutamine antagonist that shows good anticancer activity (especially in pancreatic cancer) and reduces the self-renewal potential and metastatic capacity of tumour cells. |
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产品信息
| 目录号 | A20846 |
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| 分子式 | C6H9N3O3 |
| 分子量 | 171.15 |
| CAS号 | 157-03-9 |
| SMILES | C(CC(=O)C=[N+]=[N-])C(C(=O)O)N |
| 其他名称 | Diazooxonorleucine, 6-Diazo-5-oxo-L-nor-Leucine, L-6-Diazo-5-oxonorleucine, DON |
溶解性数据
| In vitro | DMSO | Insoluble | |
| Water | 25 mg/mL (146.07 mM; Need ultrasonic) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 58.43 mL | 292.14 mL | 584.28 mL |
| 0.5 mM | 11.69 mL | 58.43 mL | 116.86 mL |
| 1 mM | 5.84 mL | 29.21 mL | 58.43 mL |
| 5 mM | 1.17 mL | 5.84 mL | 11.69 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 157-03-9 | 157-03-9 供应商 | 157-03-9 花费 | 157-03-9 生产商 | 订购 157-03-9 | 157-03-9 代理商