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7,8-Dihydroxyflavone是一种选择性的酪氨酸激酶受体B(神经营养因子/原肌球蛋白受体激酶B;TrkB)激动剂,可用于帮助识别和区分由TrkB激活介导的生理效应和细胞信号通路。涉及神经保护,记忆,血管舒张和高血压。
靶点信息
TrkB receptor | ||||
320 nM(Kd) |
In vitro | DMSO | 44 mg/mL (173.06 mM) | |
Water | Insoluble | ||
Ethanol | 1 mg/mL (3.93 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 39.33 mL | 196.66 mL | 393.33 mL |
0.5 mM | 7.87 mL | 39.33 mL | 78.67 mL |
1 mM | 3.93 mL | 19.67 mL | 39.33 mL |
5 mM | 0.79 mL | 3.93 mL | 7.87 mL |
*The above data is based on the productmolecular weight 254.24. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16123 |
---|---|
作用机制 | Agonist (激动剂) |
M. Wt | 254.24 |
Formula | C15H10O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 38183-03-8 |
Synonyms | 7,8-DHF |
SMILES | OC1=C(C2=CC=C1O)OC(C3=CC=CC=C3)=CC2=O |
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