A-395

Name: A-395
SKU: A12999
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A12999

PRC2 拮抗剂

A-395 是一种 多梳抑制复合体 2 (PRC2) 蛋白-蛋白相互作用的拮抗剂，能够强效抑制三聚体 PRC2 复合体（EZH2-EED-SUZ12）, 其半抑制浓度（IC50）为 18 nM。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
5mg	¥560.00	现货
10mg	¥875.00	现货
25mg	¥1,470.00	现货
50mg	¥2,730.00	现货
100mg	¥4,830.00	现货
*10mM 1mL in DMSO**	¥630.00	现货
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Data Sheet

SDS

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生物活性

Discription

A-395 is an antagonist of polycomb repressive complex 2 (PRC2) protein-protein interactions that potently inhibits the trimeric PRC2 complex (EZH2-EED-SUZ12) with an IC50 of 18 nM.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12999
分子式	C26H35FN4O2S
分子量	486.65
CAS号	2089148-72-9
SMILES	O=S(N1CCN(C2=CC=C([C@H]3CN(C4C(C(F)=CC=C5)=C5CC4)C[C@@H]3N(C)C)C=C2)CC1)(C)=O
其他名称	A395, A 395
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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