A-485

Name: A-485
SKU: A16830
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A16830

p300/CBP 抑制剂

A-485 是一种在体外对 p300/CBP 具有高效和选择性的 HAT 抑制剂，在 p300 TR-FRET 测试中的 IC50 为 10 nM，在 CBP TR-FRET 测试中的 IC50 为 3 nM，对于与之密切相关的 HATs 具有超过 1000 倍的选择性。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
1mg	¥560.00	现货
2mg	¥805.00	现货
5mg	¥1,190.00	现货
10mg	¥2,205.00	现货
25mg	¥3,710.00	现货
50mg	¥3,955.00	现货
100mg	¥6,860.00	现货
*10mM 1mL in DMSO**	¥1,470.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

生物活性

Discription

A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A16830
分子式	C25H24F4N4O5
分子量	536.48
CAS号	1889279-16-6
SMILES	O=C(N1CC(N([C@H](C(F)(F)F)C)CC2=CC=C(F)C=C2)=O)[C@@]3(OC1=O)CCC4=CC(NC(NC)=O)=CC=C43
其他名称	A 485, A485
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	89 mg/mL (165.9 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (165.9 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.64 mL	93.2 mL	186.4 mL
0.5 mM	3.73 mL	18.64 mL	37.28 mL
1 mM	1.86 mL	9.32 mL	18.64 mL
5 mM	0.37 mL	1.86 mL	3.73 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 A-485 | A-485 供应商 | A-485 花费 | A-485 生产商 | 订购 A-485 | A-485 代理商 | 购买 1889279-16-6 | 1889279-16-6 供应商 | 1889279-16-6 花费 | 1889279-16-6 生产商 | 订购 1889279-16-6 | 1889279-16-6 代理商