A-966492
目录号: A10019
PARP1 抑制剂
A-966492 在针对聚(ADP-核糖)聚合酶-1（PARP-1）酶的测试中显示出高效力，其抑制常数（K(i)）为1纳摩尔，而在整细胞测试中的半最大有效浓度（EC(50)）也为1纳摩尔。
顾客使用 Adooq 产品发表的高质量科研文献
A-966492 related products
生物活性
| Discription | A-966492 displayed high potency against the poly(ADP-ribose) polymerase-1 (PARP-1) enzyme with a K(i) of 1 nM and an EC(50) of 1 nM in a whole cell assay. | ||
|---|---|---|---|
| Targets |
|
产品信息
| 目录号 | A10019 |
|---|---|
| 分子式 | C18H17FN4O |
| 分子量 | 324.4 |
| CAS号 | 934162-61-5 |
| SMILES | C1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 60 mg/mL (184.98 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.83 mL | 154.13 mL | 308.26 mL |
| 0.5 mM | 6.17 mL | 30.83 mL | 61.65 mL |
| 1 mM | 3.08 mL | 15.41 mL | 30.83 mL |
| 5 mM | 0.62 mL | 3.08 mL | 6.17 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 A-966492 | A-966492 供应商 | A-966492 花费 | A-966492 生产商 | 订购 A-966492 | A-966492 代理商
| 购买 934162-61-5 | 934162-61-5 供应商 | 934162-61-5 花费 | 934162-61-5 生产商 | 订购 934162-61-5 | 934162-61-5 代理商