AAPK-25

Name: AAPK-25
SKU: A19085
Price: 560 CNY
Rating: 5 (288 reviews)

目录号: A19085

Aurora/PLK dual 抑制剂

AAPK-25 是一种强效且选择性的 Aurora/PLK 双重抑制剂，具有抗肿瘤活性，能够引起有丝分裂延迟并使细胞停留在前中期，这一过程通过生物标志物 组蛋白 H3Ser10 磷酸化 反映出来，并随后引发细胞凋亡激增。

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Grouped product items
规格	价格	库存
1mg	¥560.00	现货
5mg	¥1,435.00	现货
10mg	¥2,170.00	现货
25mg	¥3,990.00	现货
50mg	¥6,020.00	现货
100mg	¥8,785.00	现货
*10mM 1mL in DMSO**	¥1,680.00	现货
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Data Sheet

SDS

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生物活性

Discription

AAPK-25 is a potent and selective Aurora/PLK dual inhibitor with anti-tumor activity, which can cause mitotic delay and arrest cells in a prometaphase, reflecting by the biomarker histone H3Ser10 phosphorylation and followed by a surge in apoptosis.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19085
分子式	C21H13Cl2N3O2S
分子量	442.32
CAS号	2247919-28-2
SMILES	ClC1=CC(C(NC2=CC=C(C=C(C(NC3=NC=CS3)=O)C=C4)C4=C2)=O)=CC=C1Cl
其他名称	AAPK 25, AAPK25
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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