ABBV-744
目录号: A16831
BET bromodomain inhibitor
ABBV-744 是一种选择性 BDII 的 BET 溴结构域抑制剂，目前正在研究用于治疗急性髓性白血病（AML）和转移性去势抵抗性前列腺癌。
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生物活性
| Discription | ABBV-744 is a BDII-selective BET bromodomain inhibitor that is being investigated to treat AML and metastic castration-resistant prostate cancer. | |||||
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| Cell Research |
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产品信息
| 目录号 | A16831 |
|---|---|
| 分子式 | C28H30FN3O4 |
| 分子量 | 491.55 |
| CAS号 | 2138861-99-9 |
| SMILES | O=C(C(N1)=CC(C(C2=CC(C(C)(O)C)=CC=C2OC3=C(C)C=C(F)C=C3C)=CN4C)=C1C4=O)NCC |
| 其他名称 | ABBV 744, ABBV744 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 94 mg/mL (191.22 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.34 mL | 101.72 mL | 203.44 mL |
| 0.5 mM | 4.07 mL | 20.34 mL | 40.69 mL |
| 1 mM | 2.03 mL | 10.17 mL | 20.34 mL |
| 5 mM | 0.41 mL | 2.03 mL | 4.07 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 2138861-99-9 | 2138861-99-9 供应商 | 2138861-99-9 花费 | 2138861-99-9 生产商 | 订购 2138861-99-9 | 2138861-99-9 代理商