微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
Abrocitinib (PF-04965842) is a potent, orally active and selective JAK1 inhibitor, with IC50s of 29 and 803 nM for JAK1 and JAK2, respectively. Abrocitinib (PF-04965842) exhibits less active effect on TYK2 (IC50, 1.253 μM), and inhibits phosphorylation of STAT1, STAT3 and STAT5 after stimulation. Effective in autoimmune disease.
| In vitro | DMSO | 58 mg/mL (179.34 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 30.92 mL | 154.6 mL | 309.2 mL |
| 0.5 mM | 6.18 mL | 30.92 mL | 61.84 mL |
| 1 mM | 3.09 mL | 15.46 mL | 30.92 mL |
| 5 mM | 0.62 mL | 3.09 mL | 6.18 mL |
*The above data is based on the productmolecular weight 323.415. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A18318 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 323.415 |
| Formula | C14H21N5O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1622902-68-4 |
| Synonyms | PF04965842. PF 04965842 |
| SMILES | CN([C@H]1C[C@@H](NS(CCC)(=O)=O)C1)C2=C3C(NC=C3)=NC=N2 |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 Abrocitinib (PF-04965842) | Abrocitinib (PF-04965842) 供应商 | 订购 Abrocitinib (PF-04965842) | Abrocitinib (PF-04965842) 价格 | Abrocitinib (PF-04965842) 生产商 | 订单 Abrocitinib (PF-04965842) | Abrocitinib (PF-04965842) 代理商 | 购买 1622902-68-4| 1622902-68-4 供应商 | 订购 1622902-68-4 | 1622902-68-4 价格 | 1622902-68-4 生产商 | 订单 1622902-68-4 | 1622902-68-4 代理商|buy Abrocitinib (PF-04965842) | Abrocitinib (PF-04965842) Supplier | purchase Abrocitinib (PF-04965842) | Abrocitinib (PF-04965842) cost | Abrocitinib (PF-04965842) manufacturer | order Abrocitinib (PF-04965842) | Abrocitinib (PF-04965842) distributor | buy 1622902-68-4| 1622902-68-4 Supplier | purchase 1622902-68-4 | 1622902-68-4 cost | 1622902-68-4 manufacturer | order 1622902-68-4 | 1622902-68-4 distributor