ABT-737

Name: ABT-737
SKU: A10255
Price: 315 CNY
Rating: 5 (15 reviews)

目录号: A10255

Bcl-2 抑制剂

15 篇发表文献

ABT-737 是一种广谱 Bcl-2 抑制剂。IC50 值从 192 nM（前B细胞系 Hal-01）到小于 10 μM（Nalm-6、K562 和 HL-60）。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥315.00	现货
10mg	¥490.00	现货
25mg	¥910.00	现货
50mg	¥1,680.00	现货
100mg	¥2,975.00	现货
200mg	¥4,410.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用ABT-737发表的15篇文献

Jung Mo Lee, .et al. , Yonsei Med J, 2022, Jan;63(1):16-25 PMID: 34913280

AidaVarela-Moreira, .et al. , Int J Pharm, 2022, Apr 25;618:121638 PMID: 35257802

Daniel F R Boehmer, .et al. , Sci Immunol, 2021, Jul 16;6(61) PMID: 34272227

Shivani Arora, .et al. , Med, 2021, 2,1-13

Ying Ji, .et al. , Nat Commun, 2020, Aug 25;11(1):4249 PMID: 32843618

Birgit Ritschka, .et al. , Genes Dev, 2020, Apr 1;34(7-8):489-494 PMID: 32139422

Hiroki Akiyama, .et al. , Cancers, 2020, 12 (2) PMID: 32050632

Hsu CC, .et al. , Arch Oral Biol, 2020, Mar;111:104653 PMID: 31935534

Gupta VK, .et al. , Apoptosis, 2020, Feb;25(1-2):135-150 PMID: 31867678

Meikle V, .et al. , Antimicrob Agents Chemother, 2018, Nov 12. pii: AAC.01846-18 PMID: 30420480

Chauhan D, .et al. , Cell Rep, 2018, Nov 27;25(9):2354-2368.e5 PMID: 30485805

Jose Mario Gonzalez-Meljem, .et al. , Nat Commun, 2017, 8: 1819 PMID: 29180744

Zhang C, .et al. , J Biol Chem, 2017, Sep 8;292(36):15105-15120 PMID: 28673964

Eun Young Kim, .et al. , Neoplasia, 2017, Apr; 19(4): 354-363 PMID: 28319809

Masayoshi Toge, .et al. , Int J Oncol., 2015, Apr;46(4):1844-8 PMID: 25647738

生物活性

Discription

ABT-737 is a pan-Bcl-2 inhibitor. IC50 values ranged from 192 nM (the pre-B cell line Hal-01) to <10 μM (Nalm-6, K562 and HL-60).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10255
分子式	C42H45ClN6O5S2
分子量	813.4
CAS号	852808-04-9
SMILES	CN(C)CC[C@H](CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	92 mg/mL (113.1 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2%DMSO+40%PEG300+5%Tween80+53%ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.29 mL	61.47 mL	122.94 mL
0.5 mM	2.46 mL	12.29 mL	24.59 mL
1 mM	1.23 mL	6.15 mL	12.29 mL
5 mM	0.25 mL	1.23 mL	2.46 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 ABT-737 | ABT-737 供应商 | ABT-737 花费 | ABT-737 生产商 | 订购 ABT-737 | ABT-737 代理商 | 购买 852808-04-9 | 852808-04-9 供应商 | 852808-04-9 花费 | 852808-04-9 生产商 | 订购 852808-04-9 | 852808-04-9 代理商