ABT-751 (E-7010)

Name: ABT-751 (E-7010)
SKU: A10024
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A10024

Microtubule Associated 抑制剂

ABT-751 是一种抗有丝分裂剂，能够抑制微管聚合，与 β-微管蛋白结合在秋水仙素位点；在 G2M 阶段阻断细胞周期并诱导凋亡。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥805.00	现货
50mg	¥1,225.00	现货
100mg	¥1,995.00	现货
200mg	¥3,780.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription

ABT-751 is an antimitotic agent, inhibits microtubule polymerization, binds to β-tubulin on the colchine site; blocks cell cycle at G2M phase and induces apoptosis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10024
分子式	C18H17N3O4S
分子量	371.4
CAS号	141430-65-1
SMILES	COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	71 mg/mL (191.16 mM)
	Water	Insoluble
	Ethanol	12 mg/mL (32.3 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	14 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.93 mL	134.63 mL	269.25 mL
0.5 mM	5.39 mL	26.93 mL	53.85 mL
1 mM	2.69 mL	13.46 mL	26.93 mL
5 mM	0.54 mL	2.69 mL	5.39 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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