微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
ABT-751 (E-7010)是一种抗有丝分裂剂，可抑制微管聚合，并在秋水仙碱位点与β-微管蛋白结合。在G2M期阻断细胞周期并诱导凋亡。
靶点信息
| Microtubules | ||||
| In vitro (25°C) | DMSO | 71 mg/mL (191.16 mM) | |
| Water | Insoluble | ||
| Ethanol | 12 mg/mL (32.3 mM) | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W | 14 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.93 mL | 134.63 mL | 269.25 mL |
| 0.5 mM | 5.39 mL | 26.93 mL | 53.85 mL |
| 1 mM | 2.69 mL | 13.46 mL | 26.93 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.39 mL |
*The above data is based on the productmolecular weight 371.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10024 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 371.4 |
| Formula | C18H17N3O4S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 141430-65-1 |
| Synonyms | ABT751 |
| SMILES | COC1=CC=C(C=C1)S(=O)(=O)NC2=C(N=CC=C2)NC3=CC=C(C=C3)O |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
ABT-263 (Navitoclax)
ABT-263 (Navitoclax)是一种有效的Bcl-2家族抑制剂 (Bcl-2，Bcl-xL和Bcl-w的Ki
ABT-492 (Delafloxacin)
ABT-492 (Delafloxacin)是一种新的氟喹诺酮类药物，可抵抗155种需氧和171种厌氧菌。
Linifanib (ABT-869)
Linifanib (ABT-869)是一种结构新颖的有效RTK，VEGF和PDGF抑制剂，对人内皮细胞，PDGFR-β，KDR和CSF-1R的IC50分别为0.…
Obatoclax mesylate (GX15-070)
Obatoclax Mesylate (GX15-070)是一种Bcl-2拮抗剂，拮抗所有抗凋亡Bcl-2家族蛋白（平均IC50，3 umol/L），包括Mcl-1（IC5…
ABT-737
ABT-737是一种类BH3抑制剂，能同时抑制Bcl-xL，Bcl-2和Bcl-w，EC50分别为78.7 nM，30.3 nM和197.8 nM;但对Mcl-1，Bcl-B及Bf…
ABT-888 (Veliparib)
ABT-888 (Veliparib)是一种潜在的抗癌药物，可作为PARP抑制剂。
Keywords:购买 ABT-751 (E-7010) | ABT-751 (E-7010) 供应商 | 订购 ABT-751 (E-7010) | ABT-751 (E-7010) 价格 | ABT-751 (E-7010) 生产商 | 订单 ABT-751 (E-7010) | ABT-751 (E-7010) 代理商 | 购买 141430-65-1| 141430-65-1 供应商 | 订购 141430-65-1 | 141430-65-1 价格 | 141430-65-1 生产商 | 订单 141430-65-1 | 141430-65-1 代理商|buy ABT-751 (E-7010) | ABT-751 (E-7010) Supplier | purchase ABT-751 (E-7010) | ABT-751 (E-7010) cost | ABT-751 (E-7010) manufacturer | order ABT-751 (E-7010) | ABT-751 (E-7010) distributor | buy 141430-65-1| 141430-65-1 Supplier | purchase 141430-65-1 | 141430-65-1 cost | 141430-65-1 manufacturer | order 141430-65-1 | 141430-65-1 distributor