Acemetacin (Emflex)
目录号: A11692
COX 抑制剂
Acemetacin 是吲哚美辛的乙二醇酸酯。它代谢为吲哚美辛,然后作为环氧合酶的抑制剂,产生抗炎效果。
Discription | Acemetacin is a glycolic acid ester of indometacin. It is metabolized to indometacin, which then acts as an inhibitor of cyclooxygenase, producing the anti-inflammatory effects. | ||
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目录号 | A11692 |
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分子式 | C21H18ClNO6 |
分子量 | 415.82 |
CAS号 | 53164-05-9 |
SMILES | CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)OCC(=O)O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 82 mg/mL (197.2 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 57 mg/mL (137.08 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 24.05 mL | 120.24 mL | 240.49 mL |
0.5 mM | 4.81 mL | 24.05 mL | 48.1 mL |
1 mM | 2.4 mL | 12.02 mL | 24.05 mL |
5 mM | 0.48 mL | 2.4 mL | 4.81 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2