Acetyl-Calpastatin (184-210) (human)

目录号: A15290

Selective calpain 抑制剂

Acetyl-Calpastatin (184-210) (human)

Acetyl-Calpastatin (184-210) (human) Chemical Structure

CAS NO. 123714-50-1

Acetyl-Calpastatin (184-210) (human)选择性钙蛋白酶抑制剂。强烈抑制钙蛋白酶I(Ki = 0.2 nM)和II,但不抑制木瓜蛋白酶,胰蛋白酶和组织蛋白酶L(Ki = 6 uM)。增加淀粉样β蛋白(Aβ)42,Aβ40和Aβ42比率的分泌。

库存: 现货

规格 价格 数量
1 mg
¥ 1,645.00
5 mg
¥ 4,445.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Acetyl-Calpastatin (184-210) (human)选择性钙蛋白酶抑制剂。强烈抑制钙蛋白酶I(Ki = 0.2 nM)和II,但不抑制木瓜蛋白酶,胰蛋白酶和组织蛋白酶L(Ki = 6 uM)。增加淀粉样β蛋白(Aβ)42,Aβ40和Aβ42比率的分泌。
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 3.15 mL 15.73 mL 31.47 mL
0.5 mM 0.63 mL 3.15 mL 6.29 mL
1 mM 0.31 mL 1.57 mL 3.15 mL
5 mM 0.06 mL 0.31 mL 0.63 mL

*The above data is based on the productmolecular weight 3177.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A15290
作用机制 Inhibitor (抑制剂)
M. Wt 3177.65
Formula C142H230N36O44S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 123714-50-1
SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O

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