产品详情
Acetyl-Calpastatin (184-210) (human)选择性钙蛋白酶抑制剂。强烈抑制钙蛋白酶I(Ki = 0.2 nM)和II,但不抑制木瓜蛋白酶,胰蛋白酶和组织蛋白酶L(Ki = 6 uM)。增加淀粉样β蛋白(Aβ)42,Aβ40和Aβ42比率的分泌。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 3.15 mL | 15.73 mL | 31.47 mL |
0.5 mM | 0.63 mL | 3.15 mL | 6.29 mL |
1 mM | 0.31 mL | 1.57 mL | 3.15 mL |
5 mM | 0.06 mL | 0.31 mL | 0.63 mL |
*The above data is based on the productmolecular weight 3177.65. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15290 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 3177.65 |
Formula | C142H230N36O44S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 123714-50-1 |
SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O |
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