Acetyl-Calpastatin (184-210) (human)

Name: Acetyl-Calpastatin (184-210) (human)
SKU: A15290
Price: 1610 CNY
Rating: 5 (288 reviews)

目录号: A15290

Selective calpain 抑制剂

Acetyl-Calpastatin (184-210) (human)，选择性钙蛋白酶抑制剂。强烈抑制钙蛋白酶 I（Ki = 0.2 nM）和 II，但不抑制木瓜蛋白酶、胰蛋白酶和组织蛋白酶 L（Ki = 6 uM）。增加淀粉样β-蛋白（Aβ）42、Aβ40 和 Aβ42 比率的分泌。

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规格	价格	库存
1mg	¥1,610.00	现货
5mg	¥4,410.00	现货
10mg	¥8,050.00	现货
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Data Sheet

SDS

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生物活性

Discription	Acetyl-Calpastatin (184-210) (human), selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 uM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.

产品信息

目录号	A15290
分子式	C142H230N36O44S
分子量	3177.65
CAS号	123714-50-1
SMILES	CC[C@H](C)[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCSC)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CC(O)=O)NC(C)=O)[C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(N)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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