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Acoziborole (SCYX-7158) is an effective, safe and orally active treatment for human african trypanosomiasis (HAT). In the T. b. brucei S427 strain, the MIC value for SCYX-7158 is 0.6 ?g/mL.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.24 mL | 136.2 mL | 272.41 mL |
0.5 mM | 5.45 mL | 27.24 mL | 54.48 mL |
1 mM | 2.72 mL | 13.62 mL | 27.24 mL |
5 mM | 0.54 mL | 2.72 mL | 5.45 mL |
*The above data is based on the productmolecular weight 367.1. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A20642 |
---|---|
M. Wt | 367.1 |
Formula | C17H14BF4NO3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1266084-51-8 |
Synonyms | SCYX-7158, SCYX7158, SCYX 7158; AN5568, AN 5568, AN-5568 |
SMILES | O=C(NC1=CC=C2C(C)(C)OB(O)C2=C1)C3=CC=C(F)C=C3C(F)(F)F |
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